Clinical trials

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Condition / disease
Location
Status: Recruiting

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis

Sinus infections (also called acute rhinosinusitis or ARS) affect about 15% of adults each year, and are one of the top reasons people receive antibiotics in outpatient settings. Since most sinus infections are caused by viruses, many patients who take antibiotics for this condition do not actually benefit. Even though this has decreased over recent years, 70% of people are still prescribed them after a visit for ARS. Our goal is to better understand which patients truly benefit from antibiotics and which other treatment options can help people with sinus infections.

Participants needed: 3,720
Trial details
Phase: Phase 4Age: 18-75Biological sex: AllType: InterventionalSponsor: Daniel MerensteinUpdated: Mar 3, 2026Locations: 7
Eligibility criteria

"persistent" symptoms or signs compatible with ARS or sinus infection lasting fo... [+1]

allergy or intolerance to penicillin [+11]