Status: Recruiting
HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM
Study to assess the safety and efficacy of HSV-tk (gene therapy), valacyclovir, radiotherapy and chemotherapy in recurrent glioblastoma multiforme.
Participants needed: 62
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: David Baskin MDUpdated: Mar 30, 2026Locations: 1
Eligibility criteria
All patients must have biopsy proven recurrent anaplastic astrocytoma or gliobla... [+16]
Prior treatment with immunomodulatory therapy, immunotherapy, and/or gene vector... [+17]