Health Trials

Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

The purpose of this Phase 3 study is to demonstrate the efficacy of claseprubart (DNTH103) as compared to placebo in participants with chronic inflammatory demyelinating polyneuropathy (CIDP).

Participants needed: 256
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: Dianthus TherapeuticsUpdated: Jul 13, 2026Locations: 180
Eligibility criteria

Must have given written informed consent before any study-related activities are... [+12]

Clinical signs or symptoms suggestive of polyneuropathy of causes other than CID... [+10]

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Status: Recruiting

A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy

The purpose of this Phase 2 study is to evaluate the safety, tolerability, pharmacometrics, and efficacy of Claseprubart (DNTH103) in participants with multifocal motor neuropathy (MMN).

Participants needed: 36
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Dianthus TherapeuticsUpdated: Jun 23, 2026Locations: 41
Eligibility criteria

Must have given written informed consent before any study-related activities are... [+8]

History or presence of significant medical/surgical condition including any acut... [+10]

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Status: Not yet recruiting

A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE)

The purpose of this Phase 3 study is to demonstrate the efficacy, safety, and tolerability of claseprubart in participants with generalized myasthenia gravis (gMG).

Participants needed: 195
Trial details
Phase: Phase 3Age: 18-80Biological sex: AllType: InterventionalSponsor: Dianthus TherapeuticsUpdated: Jun 15, 2026
Eligibility criteria

Must have given written informed consent before any study-related activities are... [+8]

History or presence of significant medical/surgical condition including any acut... [+13]

Read more
Status: Recruiting

A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

The purpose of this Phase 3 study is to demonstrate the efficacy of claseprubart (DNTH103) as compared to placebo in participants with chronic inflammatory demyelinating polyneuropathy (CIDP).

Participants needed: 256
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: Dianthus TherapeuticsUpdated: Jun 2, 2026Locations: 168
Eligibility criteria

Must have given written informed consent before any study-related activities are... [+12]

Clinical signs or symptoms suggestive of polyneuropathy of causes other than CID... [+10]

Read more