Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH

The MOTIF@ FRESH trial will assess the safety and efficacy of "vaginal microbiome transplantation" (VMT). Healthy females will be enrolled to donate vaginal fluid which will be processed and transplanted in females with a history of recurrent bacterial vaginosis (BV), treated with antibiotics.

Participants needed: 75
Trial details
Phase: Phase 2Age: 18-25Biological sex: FemaleType: InterventionalSponsor: Douglas KwonUpdated: May 18, 2026Locations: 1
Eligibility criteria

Premenopausal females between 18 to 25 years of age who are enrolled in the FRES... [+3]

History of clinically significant vaginal, cervical, or uterine disease includin... [+24]

Status: Recruiting

Vaginal Microbiota Transplant

This is a randomized trial of vaginal microbiome transplant vs. saline placebo to restore a Lactobacillus dominant vaginal microbial community in women with recurrent bacterial vaginosis.

Participants needed: 62
Trial details
Phase: Phase 1, Phase 2Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Douglas KwonUpdated: Jul 18, 2025Locations: 1
Eligibility criteria

Premenopausal women, 18- 50 years old [+5]

History of clinically significant vaginal, cervical, or uterine disease includin... [+11]