Status: Recruiting
Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPH
The main goal of this study is to determine the effects of combination medical therapy (Riociguat and Macitentan) and balloon pulmonary angioplasty (BPA) on hemodynamics and right ventricular (RV) function (including advanced assessments of RV-pulmonary artery (PA) coupling from invasive hemodynamics) in participants with inoperable or post-PTE residual CTEPH.
Participants needed: 15
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Dr Sudarshan RajagopalUpdated: Oct 21, 2025Locations: 1
Eligibility criteria
Age ≥ 18 years' old [+5]
Moderate to severe heart disease (LVEF < 45% or severe LV Hypertrophy) [+9]