Status: Recruiting
Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders
The aim of this study is to determine the clinical spectrum and natural progression of Hereditary Spastic Paraplegias (HSP) and related disorders in a prospective multicenter natural history study, identify digital, imaging and molecular biomarkers that can assist in diagnosis and therapy development and study the genetic etiology and molecular mechanisms of these diseases.
Participants needed: 2,000
Trial details
Biological sex: AllType: ObservationalSponsor: Dr. Rebecca SchuleUpdated: May 19, 2021Locations: 13Duration: 20 Years
Eligibility criteria
Primary participant: Clinical or genetic diagnosis of HSP or a related disorder [+3]
Missing informed consent of primary or secondary participant/ healthy control/ l... [+1]