Clinical trials

2

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Condition / disease
Location
Status: Recruiting

QL1706+Lenvatinib+AG Regimen as First-line Treatment for Advanced Metastatic Pancreatic Cancer

The investigators plan to initiate a prospective, multicenter, phase II study, recruiting 80 patients with advanced pancreatic cancer who have not received prior treatment. This study aims to enhance the anti-tumor immune effect through the combination of QL1706+Lenvatinib+AG regimen, thereby improving the prognosis of patients with advanced metastatic pancreatic cancer.

Participants needed: 80
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Du JuanUpdated: Jan 2, 2026Locations: 1
Eligibility criteria

a. Age ≥18 years, ECOG performance status ≤2, and expected survival of ≥3 months... [+7]

a. Prior receipt of systemic anti-tumor treatment, such as chemotherapy, radioth... [+10]

Status: Recruiting

NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus AG Combined With PD-1 Sequential Radiotherapy as First-line Treatment of Locally Advanced Pancreatic Cancer

The purpose of the study is to evaluate the efficacy and safety of NALIRINOX combined with PD-1 synchronous sequential SBRT or AG combined with PD-1 synchronous sequential SBRT as first line systematical therapy in patients with ocally advanced pancreatic cancer.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Du JuanUpdated: Jul 10, 2024Locations: 2
Eligibility criteria

Histologically or cytologically confirmed pancreatic cancer; [+4]

1. Prior anti-tumor therapy of any kind; 2. Severe infection (>NCI CTC grade 2);...