Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

ENA-001 for Opioid Induced Respiratory Depression

This study is a Phase I clinical trial to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) profiles with single intravenous (IV) and intramuscular (IM) doses of ENA-001.

Participants needed: 36
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Enalare Therapeutics Inc.Updated: May 8, 2026Locations: 3
Eligibility criteria

Subjects must be willing to give written informed consent for the trial and able... [+22]

Current diagnosis of psychiatric disease requiring daily medication, including c... [+29]

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Status: Not yet recruiting

ENA-001 for Post Operative Respiratory Depression (PORD)

This study is a Phase II, randomized, placebo-controlled, double-blind trial in 200 subjects having general anesthesia for major elective surgery with postoperative pain management to evaluate the efficacy, safety and tolerability of ENA-001 as a therapy to prevent post operative respiratory depression.

Participants needed: 200
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Enalare Therapeutics Inc.Updated: Feb 27, 2026
Eligibility criteria

Willing to give written informed consent for the trial and willing/able to adher... [+20]

Ongoing treatment for a pre-existing chronic pain condition [+24]

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