Clinical trials

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Condition / disease
Location
Status: Recruiting

A Study of MOv18 IgE in Patients With Solid Tumours That Express Folate Receptor Alpha

EPS101-10-02 is a Phase Ib open label, multicentre clinical trial comprising of a Dose Escalation phase (Part 1) followed by a Dose Expansion phase (Part 2) of MOv18 IgE in patients with folate receptor alpha-expressing (5% or higher) platinum resistant ovarian cancer The dose escalation part of the study will primarily assess the safety and tolerability of MOv18 IgE in ascending dose cohorts, until the determination of the maximum tolerated dose (MTD) or maximum administered dose (MAD). Part 2 (dose expansion) will further assess the safety, tolerability and anti-tumour activity of MOv18 IgE.

Participants needed: 45
Trial details
Phase: Phase 1Age: 18+Biological sex: FemaleType: InterventionalSponsor: Epsilogen LtdUpdated: Apr 6, 2026Locations: 7
Eligibility criteria

Female ≥18 years of age. [+20]

Non-epithelial tumour of the ovary, the fallopian tube, or the peritoneum (inclu... [+26]