Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

The main purpose of the study is to assess whether the study drug, ERAS-0015, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with certain RAS mutations. ERAS-0015 will be given alone or in combination with other treatments.

Participants needed: 600
Trial details
Phase: Phase 1Age: 18-99Biological sex: AllType: InterventionalSponsor: Erasca, Inc.Updated: Jun 26, 2026Locations: 7
Eligibility criteria

Age ≥ 18 years [+7]

Previous treatment with a RAS inhibitor [+6]

Status: Recruiting

A Study of ERAS-4001 in Patients With Advanced or Metastatic Solid Tumors.

The main purpose of the study is to assess whether the study drug, ERAS-4001, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with certain KRAS mutations. ERAS-4001 will be given alone or in combination with other treatments.

Participants needed: 200
Trial details
Phase: Phase 1Age: 18-99Biological sex: AllType: InterventionalSponsor: Erasca, Inc.Updated: Dec 3, 2025Locations: 5
Eligibility criteria

Age ≥ 18 years [+7]

Previous treatment with a RAS inhibitor [+6]