Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain

This study aims to compare the effect of calcium-based bioceramic sealer and resin-based sealer on postoperative pain in adult patients with asymptomatic apical periodontitis undergoing root canal treatment. Asymptomatic apical periodontitis is a condition where the tissue around the tip of the tooth root is inflamed or shows a lesion on X-ray, but the patient does not experience pain. A total of 60 patients will be randomly assigned to receive root canal treatment with either the bioceramic sealer (Group A) or the resin-based sealer (Group B). Pain after treatment will be measured using a 0-10 Numeric Pain Rating Scale at 4, 24, and 48 hours post-treatment. The highest pain score reported will determine whether the treatment is considered a success (no or mild/moderate pain) or failure (severe pain). The results of this study will provide evidence on which sealer is associated with less postoperative pain, helping clinicians make informed decisions about root canal filling materials.

Participants needed: 60
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: Fatima Memorial HospitalUpdated: Dec 24, 2025Locations: 1
Eligibility criteria

Both genders. [+5]

Medically compromised patients (e.g., those with immunosuppressive or systemic d... [+5]

Status: Recruiting

Lidocaine vs. Lidocaine With Dexmedetomidine for Intravenous Regional Anesthesia (IVRA) in Upper Limb Surgery

This study compares lidocaine alone vs. lidocaine with dexmedetomidine in Intravenous regional anesthesia (IVRA) for upper limb surgery in terms of pain scores and duration of analgesia

Participants needed: 90
Trial details
Phase: Phase 4Age: 18-60Biological sex: AllType: InterventionalSponsor: Fatima Memorial HospitalUpdated: Jun 24, 2025Locations: 1
Eligibility criteria

American Society of Anesthesiology Status I [+3]

Sleep apnea [+3]

Status: Recruiting

Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section

This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section. The goal is to find the most effective combination with the fewest side effects.

Participants needed: 90
Trial details
Phase: Phase 4Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Fatima Memorial HospitalUpdated: Jun 18, 2025Locations: 1
Eligibility criteria

Elective lower segment cesarean section [+2]

Known drug allergy [+3]