Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Interscalene Brachial Plexus Block Versus Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery

Arthroscopic shoulder surgery is associated with moderate to severe postoperative pain that may delay recovery and rehabilitation. Interscalene brachial plexus block (ISB) is widely used for postoperative analgesia in shoulder surgery; however, it may be associated with complications such as phrenic nerve paralysis. The serratus posterior superior intercostal plane (SPSIP) block is a recently described fascial plane block that may provide effective analgesia while avoiding some of the limitations of ISB. This prospective, randomized, double-blind controlled trial aims to compare the analgesic efficacy of ISB and SPSIP block in patients undergoing elective arthroscopic shoulder surgery under general anesthesia. The primary outcome is total postoperative opioid consumption during the first 24 hours after surgery. Secondary outcomes include postoperative pain scores, quality of recovery, time to first rescue analgesia, rescue analgesic requirements, intraoperative opioid consumption, sensory block distribution, motor block characteristics, and block-related complications.

Participants needed: 80
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Ferit YetikUpdated: Jun 29, 2026Locations: 1
Eligibility criteria

Age between 18 and 75 years [+3]

Refusal to participate in the study [+13]

Status: Recruiting

RISS Versus SPSIP Block in Modified Radical Mastectomy

This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior intercostal plane (SPSIP) block in patients undergoing modified radical mastectomy. Postoperative pain scores, opioid consumption, rescue analgesic requirements, block-related complications, and quality of recovery outcomes will be evaluated.

Participants needed: 80
Trial details
Age: 18-75Biological sex: FemaleType: InterventionalSponsor: Ferit YetikUpdated: Jun 24, 2026Locations: 1
Eligibility criteria

Female patients aged 18-75 years [+3]

Anticoagulant therapy [+9]

Status: Recruiting

RISS Versus ESP Block in Laparoscopic Cholecystectomy

This prospective randomized controlled trial aims to compare the analgesic efficacy and effects on diaphragmatic function of bilateral erector spinae plane (ESP) block and bilateral rhomboid intercostal-subserratus plane (RISS) block in patients undergoing elective laparoscopic cholecystectomy. Postoperative pain scores, opioid consumption, diaphragmatic excursion, pulmonary function, and recovery outcomes will be evaluated.

Participants needed: 80
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Ferit YetikUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Age between 18 and 75 years [+3]

Coagulation disorders or anticoagulant therapy [+8]

Status: Recruiting

SPSIP Versus RISS Block in Volume-Preserving VATS

This prospective randomized controlled study aims to compare the effects of Serratus Posterior Superior Intercostal Plane (SPSIP) block and Rhomboid Intercostal and Subserratus (RISS) block on postoperative pain, respiratory function, and recovery quality in patients undergoing volume-preserving video-assisted thoracoscopic surgery (VATS). Eighty-four patients will be randomized in a 1:1 ratio to receive either SPSIP block or RISS block. The primary outcome is the incidence of somatic pain at the chest drain insertion site at postoperative 2 hours. Secondary outcomes include pain scores, opioid consumption, quality of recovery, diaphragmatic function, pulmonary function, rescue analgesic requirements, postoperative nausea and vomiting, and block-related complications.

Participants needed: 84
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Ferit YetikUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Patients scheduled for elective biportal video-assisted thoracoscopic surgery (V... [+3]

Use of anticoagulant or antiplatelet therapy [+11]