Clinical trials

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Condition / disease
Location
Status: Recruiting

CHOP Plus Mosunetuzumab as First Line in Patients With Richter´s Syndrome: a Phase II Study of the Spanish Group of CLL

The goal of this clinical trial is to learn if drug Mosunetuzumab works to treat Richter´syndrome . It will also learn about the safety of drug Mosunetuzumab. The main questions it aims to evaluate the efficacy of mosunetuzumab combined with CHOP (M-CHOP) after the end of induction in patients with Richter´s Syndrome who have never received thearapy What medical problems do participants have when taking drug Mosunetuzumab? Patients with Richter´s Syndrome Participants will: Take drug Mosunetuzumab+CHOP during 6 cycle and they if they are not candidate to Alothasplant continuing 11 cycles more with mosunetuzumab on monoterapy Visit the clinic once every 23weeks for checkups and tests

Participants needed: 34
Trial details
Phase: Phase 2Age: 18-79Biological sex: AllType: InterventionalSponsor: GELLC (Grupo Español de Leucemia Linfocítica Crónica)Updated: Apr 13, 2025Locations: 16
Eligibility criteria

Capable of giving signed informed consent as described in Section 13.2, which in... [+18]

Pregnant or breastfeeding or intending to become pregnant during the study or wi... [+40]