Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.

This is a Phase 2 study of GV20-0251 in combination with anti-PD-1 monoclonal antibodies (including tislelizumab and toripalimab) for the treatment of participants with unresectable, locally advanced, or metastatic solid tumors who are refractory to, intolerant of, or ineligible for standard of care.

Participants needed: 227
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: GV20 TherapeuticsUpdated: Jun 8, 2026Locations: 2
Eligibility criteria

Voluntarily signed written informed consent (ICF) prior to any study-specific pr... [+17]

Prior immunotherapy discontinued due to ≥ Grade 3 immune-related adverse events... [+24]

Status: Recruiting

Study of GV20-0251 in Participants With Solid Tumor Malignancies

This is a Phase 1 and Phase 2 study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

Participants needed: 350
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: GV20 TherapeuticsUpdated: Dec 3, 2025Locations: 3
Eligibility criteria

Before conducting any study-specific procedures, voluntarily sign an informed co... [+9]

Participants with acute leukemia or CLL [+15]

Status: Recruiting

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

This is a Phase 1/2A study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

Participants needed: 365
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: GV20 TherapeuticsUpdated: Feb 13, 2025Locations: 13
Eligibility criteria

Participants ≥18 years of age [+16]

Participant with acute leukemia or CLL (Parts A and B only) [+21]