Clinical trials

10

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Study to Evaluate the Safety of Retreatment With Restylane® Lyft With Lidocaine for Augmentation of the Chin Region

The primary objective of this study is to evaluate the safety of Restylane Lyft with Lidocaine for augmentation of the chin region 3 months after retreatment.

Participants needed: 100
Trial details
Age: 22+Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Jul 1, 2026Locations: 8
Eligibility criteria

Males or non-pregnant, non-breastfeeding females, 22 years of age or older. [+1]

Known/previous allergy or hypersensitivity to any injectable hyaluronic acid (HA... [+5]

Status: Not yet recruiting

Pharmacokinetics, Safety and Efficacy of Nemolizumab in Participants Aged 6 to 23 Months With Moderate-to Severe Atopic Dermatitis

The primary objective of the study is to assess the pharmacokinetics (PK) and safety of nemolizumab in pediatric participants (aged 6-23 months) with moderate-to-severe atopic dermatitis (AD) who are not adequately controlled with topical treatments.

Participants needed: 35
Trial details
Phase: Phase 2Age: 6-23Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Jun 22, 2026
Eligibility criteria

Participants greater than and equal to (>=) 6 to less than (<) 24 months of age... [+10]

Body weight < 5 Kilograms (kg). [+16]

Status: Recruiting

Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

The primary objective of this study is to assess the PK/PD relationship of nemolizumab in adult participants aged 18 years or above with chronic pruritus of unknown origin (CPUO) during a 16-week treatment period.

Participants needed: 50
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Jun 1, 2026Locations: 26
Eligibility criteria

Participant must be 18 years of age or older. [+9]

Known dermatologic, systemic, neurologic or psychiatric condition(s), other than... [+22]

Status: Recruiting

Real-world Experience on Using Nemolizumab in the Treatment of Moderate-to- Severe Prurigo Nodularis in Adults

The main aim of this study is to assess real-world effectiveness of nemolizumab in Prurigo nodularis (PN) as measured by investigator and patient reported outcome (PRO) in clinical practice at Month 6.

Participants needed: 600
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Galderma R&DUpdated: Jun 1, 2026Locations: 51
Eligibility criteria

Participants who, according to the treating physician's decision and in line wit... [+2]

Have contraindication(s) for the use of nemolizumab (Nemluvio®) according to the... [+3]

Status: Recruiting

A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis

The main purpose of the study is to investigate the efficacy on cutaneous thickness and the safety of Nemolizumab in adult patients with systemic sclerosis after a 52-week treatment period and to select the optimal dose for this target population.

Participants needed: 162
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Mar 31, 2026Locations: 3
Eligibility criteria

Participant must be 18 years of age or older, at the time of signing the Informe... [+12]

Anti-centromere antibody positive at screening for participants with LcSSc. [+25]

Status: Recruiting

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

The main aim of the study is to assess real-world effectiveness of nemolizumab in Atopic Dermatitis (AD) as measured by physician assessment and patient reported outcome (PRO) in clinical practice at Month 6.

Participants needed: 1,000
Trial details
Age: 12+Biological sex: AllType: ObservationalSponsor: Galderma R&DUpdated: Mar 13, 2026Locations: 108
Eligibility criteria

Participants who, according to the treating physician's decision and in line wit... [+2]

Have contraindication(s) for the use of nemolizumab (Nemluvio®) according to the... [+3]

Status: Recruiting

A Study to Characterize Human Skin Changes From Biostimulator Treatments Via Non-invasive Imaging

Adult subjects with moderate-to-severe cheek wrinkles will be treated with Sculptra for correction of fine lines and wrinkles in the cheek area.

Participants needed: 25
Trial details
Age: 45-65Biological sex: FemaleType: InterventionalSponsor: Galderma R&DUpdated: Feb 10, 2026Locations: 1
Eligibility criteria

Adult subjects aged 45-65 years old [+9]

Subjects with a history of allergy or hypersensitivity to any ingredient of the... [+3]

Status: Recruiting

A Clinical Study to Assess Histological Changes From Treatment of Poly L-lactic Acid Biostimulator on Women at Various Menopausal Stages

To assess protein expression stimulated by poly L-lactic acid (PLLA) via punch biopsy at each follow-up visits compared to Baseline.

Participants needed: 40
Trial details
Age: 22+Biological sex: FemaleType: InterventionalSponsor: Galderma R&DUpdated: Jan 15, 2026Locations: 2
Eligibility criteria

Subjects diagnosed with symmetrical, moderate-to-severe cheek wrinkles on each s... [+5]

Subjects with asymmetrical severity or unidentical cheek wrinkle score between 2... [+4]

Status: Not yet recruiting

A Prospective Pilot Study to Evaluate Safety and Effectiveness of GP0122 and GP0124 for Correction of Lines and Wrinkles in the Cheek Area

The primary objective of the study is to evaluate the safety of GP0122 and GP0124 for the correction of lines and wrinkles in the cheek area.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Jan 15, 2026
Eligibility criteria

Participants with a GCWS At Rest score of Moderate or Severe on EACH side of the... [+4]

Known/previous allergy or hypersensitivity. [+8]

Status: Recruiting

A Study to Compare the Efficacy, Safety and Pharmacokinetics of Trifarotene 50 mcg/g Cream in Chinese Subjects With Acne Vulgaris

The primary objective is to assess the efficacy of trifarotene 50 microgram per gram (mcg/g) cream versus vehicle cream when applied once daily (QD) for 12 weeks in Chinese participants with moderate facial and truncal acne vulgaris.

Participants needed: 561
Trial details
Phase: Phase 3Age: 9+Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Nov 21, 2025Locations: 1
Eligibility criteria

Male or female Chinese participants aged 9 years or older at the screening visit... [+13]

Pregnant women (positive serum pregnancy test result at the screening visit or p... [+23]