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Condition / disease
Location
Status: Not yet recruiting

Early Prophylactic Aspirin for Aneurysmal Subarachnoid Hemorrhage

This study is a multicenter, prospective, double-blind, randomized controlled trial designed to evaluate whether early prophylactic use of aspirin improves functional outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). Patients with aSAH who have undergone successful aneurysm securing will be randomly assigned to receive either aspirin plus standard care or a placebo plus standard care. The study drug will be started within 48 hours of undergone successful aneurysm securing and continued for not less than 10 days and not more than 14 consecutive days. The main goal is to compare the rate of favorable functional outcomes at 3 months between the two groups. Secondary goals include evaluating the incidence of delayed cerebral ischemia, cerebral infarction, mortality, and safety outcomes such as major bleeding events.

Participants needed: 388
Trial details
Phase: Phase 4Age: 18-80Biological sex: AllType: InterventionalSponsor: Ganzhou City People's HospitalUpdated: Jun 11, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years and ≤ 80 years. [+6]

Hunt-Hess grade 5 or WFNS grade 5 (assessed within 48 hours of SAH onset). [+26]