Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis

The purpose of this study is to determine if nicotinamide in combination with bedaquiline, pretomanid, and linezolid, is safe and effective in treating drug-susceptible pulmonary tuberculosis.

Participants needed: 165
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Gates Medical Research InstituteUpdated: Jul 2, 2026Locations: 4
Eligibility criteria

Age 18-65 years at consent [+10]

Prior TB within 3 years, >1 prior episode, or anti-TB treatment within 60 days [+10]

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Status: Recruiting

Bactericidal Activity of TBD09 in Combination With Other Drugs in Pulmonary Tuberculosis

The purpose of this study is to evaluate if TBD09 in combination with other active agents in adults with drug sensitive pulmonary tuberculosis has potential to be safe and effective.

Participants needed: 150
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Gates Medical Research InstituteUpdated: Jun 3, 2026Locations: 13
Eligibility criteria

Age 18-65 years at consent [+11]

Prior anti-TB treatment for the current TB episode within 60 days [+22]

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