Clinical trials

The purpose of this study is to conduct a proof-of-concept intervention of daily inhibitory control (IC) training. Aim 1 is to examine the feasibility, acceptability, and barriers of an IC training EMI in adolescents' daily life. Aim 2 is to evaluate the efficacy of IC training for modifying the hypothesized intervention mechanism: food-related IC and eating regulation. In the study, participants will: Complete questionnaires and cognitive tasks Receive a short nutrition education Complete three weeks of daily brain games on your phone

The goal of this intervention trial is to evaluate the effectiveness the online training program Dementia Education and Resources for Action (DERA) in improving Alzheimer's disease and related dementia-(ADRD) knowledge, stigma, and service-related self-efficacy among community health workers (CHWs). We hypothesize that participants who have completed the DERA will have improved ADRD knowledge and self-efficacy in related service and reduced stigma against ADRD and people affected.

The purpose of this study is to test WECARE, a seven-week multimedia intervention designed to reduce psychosocial distress and provide education and support for caregivers. This study will include Chinese American family caregivers of persons living with Alzheimer's disease and related dementias. Participants will engage with digital learning materials and supportive resources over the course of the program. The goal is to determine whether this approach improves caregiver well-being and reduces stress related to caregiving.

The goal of this clinical trial is to evaluate how a conversational method of collecting medical history affects patients' perceptions and experiences compared to clinical care as usual. This conversational AI intake system collects medical history information, can be completed by participants at home, and do not disrupt routine clinical care. The primary questions this study aims to answer are: 1\) Does conversational intake affect patients' perceptions of empathy during their clinical interactions? This will be a prospective study that follows a cohort of participants for four (4) months after engaging with the AI intake system. Because each participant serves as his/her own control, both comparators will be administered within-subject, and the order of exposure (AI intake vs. usual care) will be randomized to minimize sequence effects. After completing the AI intake method, participants will rate their experience, particularly in terms of empathy and compare it to their usual interactions with their own clinicians.

The aCT Study will develop, implement and evaluate a community health worker (CHW) integrated model of care delivery for older adults that is senior center based. CHW services will be available for older adult participants at three centers, 4 hours per week for 4 months. Three centers will continue usual services. Researchers will compare blood pressure, physical activity levels, fruit/vegetable consumption and psychosocial outcomes across groups before and after the intervention.

The purpose of this study is to assess the effectiveness of the Probation/Parole and Reentry Coach Application (PARCA)-a mobile application that allows justice-involved people to set and manage personal goals to support sustained, successful community supervision. Through this study, we aim to conduct surveys and interviews aimed to gain a better understanding of ways to improve the substance use treatment process, connections between clients and officers, and goal selection and achievement for clients using the PARCA app

The goal of the proposed research is to design a peer-based community intervention focused on addressing HIV stigma, and peer support to increase PrEP initiation in Prince George's County, MD. Participants will attend intervention events focused on stigma reduction and building community. Researchers will compare intervention and control group participants to see if there in a difference in PrEP initiation and adherence.

The purpose of this proposed study is to investigate both the acute and chronic response of frontal plane knee moment after gait retraining and to assess the effects on the biomechanics of the contralateral side. Fifty-one patients diagnosed with tibiofemoral joint osteoarthritis (TFJ OA) will be recruited to participate in the proposed study. Participants will complete baseline trials to assess gait kinematic and kinetic parameters. Following baseline, each participant will perform six conditions of the foot progression gait or three conditions of the trunk lean gait modifications to determine which strategy is most effective in reducing frontal plane knee moment. Participants will then be randomized to either the control or experimental group based on their identified preferred strategy. Participants will complete eight gait retraining sessions using patient-specific gait modifications (tailored foot progression and tailored lateral trunk lean), or normal gait (control) during the training period. A fading feedback design will be implemented. Real-time haptic biofeedback will be provided on every step during the first two weeks and reduced by 25% every subsequent two weeks. No feedback will be provided during baseline and at testing sessions. Measures of pain and function will also be collected at all testing sessions. Variables of interest include ankle, knee, hip sagittal and frontal plane moments. In addition, sagittal and frontal plane impulse will also be assessed. Descriptive statistics will be calculated for foot progression angle, trunk lean angle, frontal and sagittal plane hip, knee, and ankle angles as well as moments. Descriptive statistics for frontal plane knee impulse will also be calculated. A multivariate analysis of variance (MANOVA) will be conducted to compare frontal plane knee moment, frontal plane knee impulse and the absolute sagittal plane moment will be compared across three groups at four different time points. Repeated measures analysis of variance (ANOVA) will be conducted to compare both sagittal and frontal plane joint biomechanics for the contralateral limb. The p-value will be set at .05.