Clinical trials

7

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Associations of Cranial Outcomes and Parental Expectations and Satisfaction

This study aims to investigate the association between objective cranial morphological changes and parental expectations and satisfaction in infants undergoing treatment with a cranial remolding orthosis (CRO). Infants diagnosed with positional cranial deformities and prescribed CRO treatment will be included. Cranial morphological outcomes will be assessed using standardized cranial measurements obtained before and after the treatment period. Parental treatment expectations will be evaluated prior to the initiation of CRO therapy using the Treatment Expectation Questionnaire (TR.TEX-Q), while parental satisfaction with the device and treatment process will be assessed at the end of treatment using the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST). The primary objective of the study is to examine the relationships between changes in cranial morphology and parental expectations and satisfaction scores. Secondary objectives include exploring the association between baseline expectations and post-treatment satisfaction. The findings are expected to provide insight into how objective treatment outcomes align with family-reported perceptions in cranial remolding orthosis therapy.

Participants needed: 20
Trial details
Age: 3-18Biological sex: AllType: ObservationalSponsor: Gulhane School of MedicineUpdated: Jan 26, 2026Locations: 1Duration: 1 Month
Eligibility criteria

Infants diagnosed with positional cranial deformities (e.g., plagiocephaly, brac... [+5]

Infants with neurological disorders, genetic syndromes, or congenital conditions... [+5]

Status: Recruiting

A Comparison of Myoelectric and Bionic Hands

This observational study aims to compare myoelectric and bionic hands in terms of upper extremity function, body image and satisfaction. The main questions it aims to answer are: \- Does upper extremity function differ between bionic and myoelectric hands? The main questions it aims to answer are: Does upper extremity function differ between bionic and myoelectric hands?

Participants needed: 20
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Gulhane School of MedicineUpdated: Jan 16, 2026Locations: 1Duration: 1 Day
Eligibility criteria

Aged 18 to 65 years [+4]

Presence of bilateral or multiple limb amputations [+2]

Status: Recruiting

Preoperative Pelvic Floor Muscle Training in Female Urinary Incontinence

Pelvic floor muscles (PFM) play a crucial role in supporting pelvic organs and maintaining continence. Weakness in these muscles can lead to dysfunctions such as pelvic organ prolapse, urinary incontinence (UI), and sexual or anorectal disorders. UI, defined as the involuntary loss of urine, is common globally and classified as stress, urge, or mixed incontinence. Stress urinary incontinence (SUI) - the most prevalent type among women - occurs during activities that increase intra-abdominal pressure. Risk factors include female sex, aging, obesity, smoking, chronic constipation, previous gynecological surgeries, and childbirth. Treatment options for SUI include conservative and surgical methods. Pelvic floor training (PFT), first described by Arnold Kegel in 1948, is a conservative approach that strengthens PFM and alleviates symptoms. Although surgery is often used for SUI, with over 200 procedures described, this study aims to evaluate the preoperative effectiveness of intensive PFT in women with SUI. It will assess changes in muscle function and symptoms before surgery, guiding pelvic rehabilitation strategies to potentially reduce surgical burden and improve outcomes.

Participants needed: 60
Trial details
Age: 18-65Biological sex: FemaleType: InterventionalSponsor: Gulhane School of MedicineUpdated: May 8, 2025Locations: 1
Eligibility criteria

Being a woman between the ages of 18-65 [+6]

Not volunteering to participate [+6]

Status: Recruiting

Can Lumbar Mulligan Mobilization Improve Gait, Balance, and Trunk Position Sense After Stroke?

Stroke is a pathology caused by disturbances in the brain's arterial circulation, leading to high morbidity rates. Individuals who experience a stroke often face neurological impairments such as motor, sensory, and cognitive dysfunctions, which negatively impact muscle strength, postural control, sensation, and gait, reducing their independence in daily activities. Balance deficits in stroke patients increase the risk of falls and contribute to a fear of falling. Improving balance control is a key goal in rehabilitation. The importance of the trunk in balance control and rehabilitation is well-established, as it plays a central role in maintaining stability. In individuals with restricted lumbar mobility, weakened trunk muscles and altered muscle activation can lead to a reduction in proprioception, hip strategy, and spinal stabilization, further impairing balance. Combining conventional exercise approaches with other rehabilitation techniques has been shown to yield more effective outcomes. This study aims to investigate the effects of Mulligan-based lumbar spine mobilization on balance, trunk position sense, and gait in individuals with stroke.

Participants needed: 40
Trial details
Age: 30-65Biological sex: AllType: InterventionalSponsor: Gulhane School of MedicineUpdated: Mar 20, 2025Locations: 1
Eligibility criteria

Diagnosed with stroke by a neurologist. [+5]

History of musculoskeletal disorders affecting the spine (e.g., cancer, scoliosi... [+3]

Status: Recruiting

Examination of the Effect of Nocturia on Pelvic Floor Symptoms, Sleep Parameters and Quality of Life in Women with Urinary Incontinence

Urinary incontinence (UI), a common issue, is the involuntary leakage of urine that negatively affects individuals socially, physically, and psychologically, leading to a decreased quality of life. Nocturia, which is often seen alongside UI, has similar adverse effects. Nocturia refers to the number of urinations during the main sleep period, and it should be accompanied by the intention to fall back asleep after waking up. Nocturia can arise from factors such as sleep disorders and circadian rhythm disturbances. The circadian rhythm regulates the body's biological functions, and this rhythm varies from person to person, creating chronotypes. There is a strong relationship between sleep and nocturia because nocturia leads to deep sleep loss, an increased risk of metabolic diseases, decreased sleep quality and sleep efficiency, and an increase in the number of awakenings after sleep onset. It is necessary to distinguish whether nocturia, which has a comprehensive impact, affects pelvic floor symptoms, chronotype, sleep quality, fatigue, sleepiness, and quality of life in women with UI. Therefore, the aim of this study is to examine the effect of nocturia on pelvic floor symptoms, chronotype, sleepiness, sleep quality, fatigue, and quality of life in women with UI.

Participants needed: 102
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Gulhane School of MedicineUpdated: Mar 10, 2025Locations: 1
Eligibility criteria

Being 18 years of age or older [+6]

Diagnosis of a sleep disorder [+30]

Status: Recruiting

Examining the Relationship Between Physical Activity Levels and Chronotype Tendencies in Individuals With Alcohol Dependence

Alcohol use disorders are characterized by excessive alcohol consumption and loss of control and are associated with high mortality and disease burden. The relationship between physical activity and alcoholism is complex, and low physical activity has been shown to be linked to alcohol consumption. Additionally, individuals' circadian rhythms (chronotypes) may influence alcohol consumption habits; Evening-type individuals are more likely to consume alcohol. This study aims to examine the relationship between physical activity levels and chronotype trends in individuals with alcohol addiction.

Participants needed: 207
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Gulhane School of MedicineUpdated: Feb 27, 2025Locations: 1
Eligibility criteria

Age: Being between 18-65 years old. [+2]

Active Psychiatric Diseases: For example, individuals with active psychiatric di... [+1]

Status: Not yet recruiting

Acupressure Mat on Perceived Stress, Sleep Quality and Premenstrual Symptoms

Purpose of the study: To examine the effect of acupressure mat on perceived stress, sleep quality and premenstrual symptoms in students with premenstrual syndrome. Hypotheses of the study; In the post-test and follow-up test between students who were applied acupressure mat and those who were applied plain mat; H10: There is no difference in terms of severity of premenstrual symptoms. H20: There is no difference in terms of perceived stress. H30: There is no difference in terms of sleep quality.

Participants needed: 42
Trial details
Biological sex: FemaleType: InterventionalSponsor: Gulhane School of MedicineUpdated: Oct 16, 2024
Eligibility criteria

Using medication and/or non-medical methods to cope with PMS [+2]

Participants wanting to withdraw from the study at any stage of the study [+3]