Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Shrinking the Anterior Border of CTV2 for Nasopharyngeal Carcinoma to Reduce the Radiation of Nasal Cavity

This is a an open-label, non-inferiority, multicenter, randomized phase III trial aimed to explore the efficacy and safety of shrinking the anterior border of CTV2 in nasopharyngeal carcinoma patients without tumor invasion into the posterior nasal aperture.

Participants needed: 550
Trial details
Phase: Phase 3Age: 18-70Biological sex: AllType: InterventionalSponsor: Hai-Qiang Mai,MD,PhDUpdated: Jul 18, 2025Locations: 5
Eligibility criteria

Newly diagnosed, histologically confirmed non-keratinizing carcinoma (WHO classi... [+10]

Keratinizing squamous cell carcinoma (WHO Type I) or basaloid squamous cell carc... [+8]

Status: Recruiting

Reduced Dose Radiotherapy vs Standard Dose Radiotherapy for Early Stage Nasopharyngeal Carcinoma

This study investigates whether administering reduced dose is non-inferior to standard dose radiotherapy in terms of 3-year locoregional relapse-free survival (LRRFS) rate for stage I nasopharyngeal carcinoma patients who are sensitive to radiotherapy.

Participants needed: 342
Trial details
Phase: Phase 3Age: 18-70Biological sex: AllType: InterventionalSponsor: Hai-Qiang Mai,MD,PhDUpdated: Apr 22, 2025Locations: 1
Eligibility criteria

Age 18-70, regardless of sex. [+8]

Histologically confirmed keratinizing squamous cell carcinoma (WHO I). [+10]

Status: Not yet recruiting

The Children and Adolescents Nasopharyngeal Carcinoma Survivor Study

The Children and Adolescents Nasopharyngeal Carcinoma Survivor Study will investigate the long-term effects of nasopharyngeal carcinoma (NPC) and its associated therapies. A prospective and retrospective cohort study will be conducted through a multi-institutional collaboration. This project will study children and adolescents exposed to specific therapeutic modalities, including radiation, chemotherapy, and/or surgery, who are at increased risk of late-occurring adverse health outcomes. A group of sibling controls will be identified and data collected for comparison purposes.

Participants needed: 1,000
Trial details
Age: Up to 21Biological sex: AllType: ObservationalSponsor: Hai-Qiang Mai,MD,PhDUpdated: Aug 28, 2018
Eligibility criteria

Patients or their siblings must be informed of the investigational nature of thi... [+1]

Already involved in other blind clinical trial. [+1]