Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement

One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which makes the results difficult to generalize.

Participants needed: 14
Trial details
Age: 18-26Biological sex: AllType: InterventionalSponsor: Hama UniversityUpdated: Sep 15, 2025Locations: 1
Eligibility criteria

The patient's age (18-26). Severe or very severe irregularity of the upper incis... [+3]

• The presence of any systemic disease that affects orthodontic dental movement. [+5]

Status: Recruiting

Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates

Patients with skeletal class II malocclusion who have a retracted lower jaw will be treated in this study. The efficacy of clear Plates in the treatment of Skeletal Class II Malocclusion will be assessed. The skeletal, dental and soft tissues changes resulted by this intervention will be studied and compared with the results of Traditional treatment with fixed appliances.

Participants needed: 32
Trial details
Age: 10-13Biological sex: AllType: InterventionalSponsor: Hama UniversityUpdated: Sep 15, 2025Locations: 1
Eligibility criteria

- Patients with mixed dentition at age 10.5-13 years. [+5]

-Patients with periodontal disease. [+8]

Status: Recruiting

Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy

Patient with class ii division 1 malocclusion who have mild increased overjet will be treated in this study. The efficacy of clear aligners in the treatment of Class II division 1 Malocclusion Using Intermaxillary Elastics will be assessed. The skeletal, dental and soft tissues changes resulted by this intervention will be studied and compared with the results of Traditional treatment with fixed appliances. There are two group: 1. a group of patients in which participants will be undergo to the clear aligners with class ii elastics. 2. a group of patients in which participants will be undergo to the traditional fixed appliances with class ii elastics.

Participants needed: 24
Trial details
Age: 15-20Biological sex: AllType: InterventionalSponsor: Hama UniversityUpdated: Sep 15, 2025Locations: 1
Eligibility criteria

- Patients with permanent occlusion at age 15-20 years. [+6]

Patients with periodontal disease. [+7]

Status: Recruiting

Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners

Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will be assessed along with patient's pain and satisfaction. There are two groups: 1. a group of patients in which participants will be received treatment with the traditional clear aligners technique in addition to a micro-osteoperforations technique. 2. a group of patients in which participants will be received treatment with the traditional clear aligners technique alone

Participants needed: 30
Trial details
Age: 18-26Biological sex: AllType: InterventionalSponsor: Hama UniversityUpdated: Sep 15, 2025Locations: 1
Eligibility criteria

Completion of permanent dentition (except third molars) [+3]

• Systematic diseases that could affect bone and tooth movement and no contraind... [+3]