Clinical trials

7

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Three-Dimensional Bone Augmentation of Severely Atrophied Posterior Mandibular Alveolar Ridges Using Customized-3D Zirconia Barriers Versus Pre-bent Titanium Mesh

Zirconia can be considered as an alternative and innovative material suitable for GBR because it has high biocompatibility, together with a scarce tissue integration. Zirconia barriers could be a predictable and alternative barrier material for GBR in terms of (i) biocompatibility, (ii) ease of use and removal, (iii) exposure management, (iv) bone regeneration outcomes.

Participants needed: 16
Trial details
Age: 20-50Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

Patients are systemically medically free according to the American Society of An... [+5]

Smoker (> 25 cigarettes/ day). [+6]

Status: Not yet recruiting

Immediate Implant Placement Using the Socket Shield Technique in Maxillary Esthetic Zone

Immediate implant placement in the esthetic zone is an approach that helps preserve soft and hard tissue architecture. However, post extraction bone resorption is still a significant challenge. The socket shield technique (SST) has emerged as a promising way for preserving the buccal plate, potentially improving implant stability and reducing radiographic bone loss. The aim of the present study is to evaluate the clinical and radiographic outcomes of the socket shield technique in the maxillary esthetic zone by assessing implant stability, radiographic bone loss as well as esthetic outcome over a specified follow-up period.

Participants needed: 8
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Jul 24, 2025Locations: 1
Eligibility criteria

Patients with a non-restorable maxillary tooth in the aesthetic zone indicated f... [+2]

Patients with extraction socket Type II or III, with defect in the buccal plate. [+9]

Status: Not yet recruiting

Hydrodynamic Piezoelectric Technique in Internal Sinus Lift

Background: The use of hydrodynamic piezoelectric techniques for trans crestal / internal sinus lift with simultaneous implant placement has gained popularity as a safe and minimally invasive technique for managing the posterior edentulous maxilla, particularly in cases with sinus pneumatization. This method offers a controlled elevation of the Schneiderian membrane while reducing the risk of perforation compared to conventional techniques. Additionally, it minimizes postoperative discomfort and oedema, leading to better acceptance and satisfaction by the patients. In contrast to traditional osteotome tapping procedures, the hydrodynamic piezoelectric technique enhances surgical outcomes while preserving vital anatomical structures, making it a superior alternative in implant dentistry. This study aims to evaluate the use of the hydrodynamic piezoelectric technique in internal sinus lifting with simultaneous implant placement in comparison to the conventional osteotome technique.

Participants needed: 22
Trial details
Age: 30-50Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Jul 1, 2025Locations: 1
Eligibility criteria

Patients with edentulous free end or bounded posterior maxilla that require impl... [+3]

Patients with residual alveolar bone height less than 5 mm according to the tomo... [+5]

Status: Not yet recruiting

Diode Laser Photocoagulation With Immediate Implant Placement

Placement of an immediate implant is becoming popular because of its potential in minimizing the treatment time and enhancing the patient comfort and esthetic outcomes. It is crucial to maintain adequate thickness of labial bone with the establishment of a stable and healthy gingival seal around the implant abutment to prevent the invasion of bacteria and peri-implant inflammation. Diode lasers have been developed as a promising tool in dentistry, providing a precise manipulation and photocoagulation effect that may have a positive influence on both bone remodeling and soft tissue healing. This study aims to evaluate the effectiveness of the utilization of diode laser photocoagulation with immediate implant placement and customized healing abutment in the maxillary esthetic zone.

Participants needed: 8
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Jul 1, 2025Locations: 1
Eligibility criteria

A severely carious tooth that cannot be restored. [+5]

Patients with extraction socket Type II or III, with buccal plate defects. [+6]

Status: Recruiting

Clinical Performance and Acceptance of Bioflx Crowns

Treating pediatric patients with early childhood caries can be challenging. For clinicians, managing a young child while ensuring high-quality treatment is difficult. It is essential to have the best equipment and materials available. Today, aesthetics are crucial in managing decayed teeth, with zirconia crowns often preferred for their visual appeal, although they require substantial preparation. The newly developed Bioflx crown, combining stainless steel and zirconia properties, offers an alternative solution.

Participants needed: 62
Trial details
Age: 4-8Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Nov 7, 2024Locations: 1
Eligibility criteria

A child with primary molars is indicated for full coverage.

Children with any systemic disease [+3]

Status: Recruiting

Magnetic Mallet and Densah Bur for Crestal Sinus Left

Background: Implant placement in the posterior maxilla is problematic procedure, not only due to inferior properties of bone but also due to loss of vertical bone height, which happens after extraction of posterior teeth. When the required additional height is few millimeters, indirect transcrestal sinus lifting is recommended. Aim: The aim of this study is to evaluate Densah bur versus Magnetic mallet in transcrestal sinus lifting procedure in edentulous molar and premolar maxillary region.

Participants needed: 18
Trial details
Age: 30-60Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Nov 6, 2024Locations: 1
Eligibility criteria

Patient seeking replacement of missing maxillary posterior teeth by dental impla... [+4]

Uncontrolled Diabetes. [+7]

Status: Recruiting

Digital Versus Conventional Impression on Discomfort and Dental Anxiety Among Preschoolers

Background: Taking alginate impressions for preschoolers is challenging and might be disturbing for them. Therefore, intraoral scanners are suggested as a better alternative to the conventional alginate impression. Objectives: The present study aims to evaluate and compare the level of patients' discomfort, dental anxiety, gag reflex, behavior and time required for taking alginate impressions with that of intraoral scanning. Materials and methods: The study will be a randomized, controlled clinical trial, parallel design. A total of 666 pediatric dental patients aged from 4-6 years will be selected from the outpatient clinic of the of Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Alexandria University. Participants will be allocated into 2 groups. Children in the first group will receive digital impressions by an intraoral scanner, while those of the second group will receive conventional alginate impressions. Patients' discomfort will be evaluated by a modified VAS index supported with emojis. Dental anxiety will be evaluated using Facial Image Scale (FIS). Gag reflex will be assessed by Gag Severity Index (GSI). Child's behavior towards the impression technique in the 2 groups will be evaluated using Venham's Behavior rating scale. Time taken to complete the procedures will be recorded using a digital stopwatch.

Participants needed: 66
Trial details
Age: 4-6Biological sex: AllType: InterventionalSponsor: Hams Hamed AbdelrahmanUpdated: Oct 2, 2024Locations: 1
Eligibility criteria

Children with scores of 3 or 4 during preoperative assessments according to the... [+2]

Any physical or mental disability, or psychological problems. [+1]