Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

DEC003M in Prostate Cancer

This is an open-label, multicenter Phase 1 study of DEC003M, in patients with advanced stage prostate cancer. The study consists of a dose-escalation phase to determine the dose for expansion, followed by a dose-expansion phase to evaluate preliminary antitumor activity, safety, and pharmacokinetics.

Participants needed: 110
Trial details
Phase: Phase 1Age: 18+Biological sex: MaleType: InterventionalSponsor: Hangzhou DAC Biotechnology Co., Ltd.Updated: Jun 22, 2026Locations: 4
Eligibility criteria

At the time of informed consent, be ≥18 years of age. [+8]

History of other malignancies. [+12]

Status: Recruiting

A Study of DXC006 in Patients With Advanced Solid Tumors and Hematologic Malignancies

This is a phase I, open-label, first-in-human clinical study designed to evaluate the safety, tolerability, MTD, DLT, RP2D, the PK characteristics, preliminary anti-tumor activity, the immunogenicity of DXC006 in patients with a variety of solid tumors, including small cell lung cancer, multiple myeloma, and neuroblastoma, and hematological malignancies.

Participants needed: 280
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Hangzhou DAC Biotechnology Co., Ltd.Updated: Jun 22, 2026Locations: 5
Eligibility criteria

The patient voluntarily signed the informed consent form and followed the protoc... [+9]

Within 14 days before the first dose: received plasmapheresis; Treatment with >... [+20]

Status: Not yet recruiting

A Study of DXC006 With Immune Checkpoint Inhibitors or Platinum for Small Cell Lung Cancer.

This is a Phase Ib/II, open-label clinical study designed to evaluate the safety, tolerability, preliminary anti-tumor activity, recommended Phase 2 dose (RP2D), pharmacokinetic (PK) characteristics, and immunogenicity of DXC006 in combination with an immune checkpoint inhibitor (ICI) or platinum-based chemotherapy in patients with small cell lung cancer (SCLC).

Participants needed: 200
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Hangzhou DAC Biotechnology Co., Ltd.Updated: May 29, 2026Locations: 1
Eligibility criteria

Voluntarily signed informed consent and willingness to comply with the protocol... [+8]

Histologically or cytologically confirmed combined SCLC, NSCLC, sarcomatoid carc... [+20]

Status: Recruiting

A Study of DXC014 in Patients With Advanced Solid Tumors.

This is a phase I, open-label, first-in-human clinical study designed to evaluate the safety, tolerability, MTD, DLT, RP2D, the PK characteristics, preliminary anti-tumor activity, the immunogenicity of DXC014 in patients with Advanced Solid Tumors.

Participants needed: 150
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Hangzhou DAC Biotechnology Co., Ltd.Updated: Apr 24, 2026Locations: 3
Eligibility criteria

Voluntarily sign the informed consent form and comply with the protocol requirem... [+2]

Within 14 days prior to the first dose: Underwent plasmapheresis; received syste... [+17]

Status: Recruiting

A Study of DXC008 in Patients With Prostate Cancer and Other Solid Tumors

This is a phase I, open-label, first-in-human clinical study designed to evaluate the safety, tolerability, MTD, DLT, RP2D, the PK characteristics, preliminary anti-tumor activity, the immunogenicity of DXC008 in patients with prostate cancer and other solid tumors such as Ewing sarcoma.

Participants needed: 110
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Hangzhou DAC Biotechnology Co., Ltd.Updated: Apr 24, 2026Locations: 3
Eligibility criteria

Those who voluntarily sign the ICF and follow the protocol requirements. [+15]

Within 14 days prior to the first dose: Have undergone plasmapheresis, treated w... [+22]