Clinical trials

7

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparing Myopia Treatments in Youth: Defocus Spectacles, Glasses, and Ortho-K

The research project titled "A Comparative Study on the Clinical Efficacy, Quality of Life, and Cost of Use of Peripheral Defocus Spectacles, Frame Glasses, and Orthokeratology Lenses in Myopic Children and Adolescents" aims to evaluate different non-surgical myopia correction methods in children. It focuses on assessing the impact of peripheral defocus spectacles, frame glasses, and orthokeratology lenses on the quality of life, clinical effectiveness, and costs associated with each method. The study is a prospective cohort study involving 90 children aged 8-17 years with myopia ranging from -1.00D to -6.00D. It aims to compare the psychological, social, and educational aspects of these correction methods, alongside their costs and clinical outcomes over a period of one year.

Participants needed: 90
Trial details
Age: 7-17Biological sex: AllType: ObservationalSponsor: He Eye HospitalUpdated: Mar 23, 2026Locations: 1
Eligibility criteria

Children aged 7-17 years. [+4]

History of strabismus, amblyopia, refractive disparity or retinal diseases [+3]

Status: Not yet recruiting

Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients With Dry Eye After LASIK

The prevalence of refractive ametropia is rising year by year. Refractive surgery has become the main approach for adults to correct refractive ametropia, and postoperative complications have aroused extensive attention from clinicians. Dry eye after refractive surgery is one of the postoperative complications, which is an important cause of affecting the postoperative visual quality and satisfaction of patients. It was reported that 3% diquafosol (DQS) and 0.1% hyaluronic acid (HA) can relieve dry eye symptoms. This study aims to compare the efficacy of 3% DQS and 0.1% HA in treating dry eye after LASIK

Participants needed: 140
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: He Eye HospitalUpdated: Aug 1, 2025
Eligibility criteria

History of LASIK surgery for more than six months [+2]

Suspected of having keratoconus, a definite diagnosis of keratoconus or another... [+3]

Status: Not yet recruiting

Precision Lifestyle Interventions Guided by Continuous Glucose Monitoring: Impact on Glycemic Outcomes in Type 2 Diabetes Mellitus

This study is an interventional research. Through scientific evaluation, it explores the effect of precise lifestyle intervention based on CGM data on the control of chronic type 2 diabetes mellitus. By formulating a safe and effective precise lifestyle intervention plan, lifestyle medicine is integrated into the management of chronic diseases. Through multidimensional evaluations, it is expected to improve patients' self-management ability and provide a reference for the development of chronic diabetes management.

Participants needed: 200
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: He Eye HospitalUpdated: May 7, 2025
Eligibility criteria

Comply with the diagnostic criteria for T2DM in the 'Clinical guidelines for pre... [+4]

Pregnant women, lactating women, and women of childbearing age who do not wish t... [+7]

Status: Not yet recruiting

Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients with Dry Eye After Trans-PRK

The prevalence of refractive ametropia is rising year by year. Refractive surgery has become the main approach for adults to correct refractive ametropia, and postoperative complications have aroused extensive attention from clinicians. Dry eye after refractive surgery is one of the postoperative complications, which is an important cause of affecting the postoperative visual quality and satisfaction of patients. It was reported that 3% diquafosol (DQS) and 0.1% hyaluronic acid (HA) can relieve dry eye symptoms. This study aims to compare the efficacy of 3% DQS and 0.1% HA in treating dry eye after Trans-PRK

Participants needed: 76
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: He Eye HospitalUpdated: Feb 28, 2025
Eligibility criteria

Age 18-40 years. [+4]

Suspected of having keratoconus, a definite diagnosis of keratoconus, or another... [+5]

Status: Not yet recruiting

Effect of Spectacle Distribution to Myopic Secondary School Students in Rural Communities of Liaoning Province on Communities Academic High School Enrolment

To determine whether provision of free spectacles to rural-dwelling Chinese secondary school students with visually-significant refractive error, together with a teacher-based incentive to promote their use, increases the proportion of children going on to academic high school, as opposed to dropping out or pursuing a vocational track.

Participants needed: 1,980
Trial details
Age: 11-16Biological sex: AllType: InterventionalSponsor: He Eye HospitalUpdated: Dec 4, 2024Locations: 1
Eligibility criteria

Year 1 students (about 12-15 years old) from schools in county-level cities and... [+3]

Hyperopia ≥2.00 D [+1]

Status: Not yet recruiting

Effect of Artificial Tears on Ocular Biometry Parameters

Due to the instability of the tear film, the biometry often needs to be done multiple times in a clinical environment. The high variability of both short-term and long-term repeatability in keratometry of dry eyes is well-known. Consequently, enhancing the condition of the eye surface in individuals with dry eyes will result in improved precision when choosing the power of intraocular lenses (IOLs). This prospective and before-and-after self-control study will recruit 100 patients.

Participants needed: 100
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: He Eye HospitalUpdated: Oct 24, 2024
Eligibility criteria

The eyes cannot fixate on the fixation lamp (such as children, nystagmus disease... [+8]

Status: Not yet recruiting

Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye

Investigate the effect of 3% Diquafosol on tear film and vision-related quality of life in dry eye patients wearing orthokeratology lenses(OK lens), and to provide reference for clinical treatment.This prospective, open label study will include 60 eyes of 30 OK lens related dry eye patients.Participants will receive 3% Diquafosol ophthalmic solution. The dosage for both drugs will be one drop, six times per day for 4 weeks. Pediatric Refractive Error Profiletear(PREP), tear film lipid layer (TFLL),non-invasive breakup time (NITBUT), corneoconjunctival staining score (CS), tear meniscus height (TMH), objective visual quality,ocular surface disease index (OSDI) will be assessed and compared at baseline, day-14, and day-28

Participants needed: 30
Trial details
Age: 8-18Biological sex: AllType: InterventionalSponsor: He Eye HospitalUpdated: Aug 12, 2024
Eligibility criteria

Age 8-18 years old [+4]

Suffering from allergic or autoimmune disease associated with dry eye of the par... [+4]