Clinical trials

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Condition / disease
Location
Status: Recruiting

Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)

The goal of this clinical trial is to prospectively document to what extent the OSC/SS prophylactic laser retinopexy procedure works to prevent retinal detachment in SS in children and adults. Researchers will compare the OSC/SS procedure in SS to the natural progression of SS to see to what extent the OSC/SS procedure works to prevent retinal detachment. Participants will: * Have the OSC/SS procedure in one or both eyes * Have eye tests * Have genetic testing for SS as needed * Visit the study center 9 times over 5 years for checkups and tests * Have data for the untreated fellow-eye collected and used as study data if available

Participants needed: 500
Trial details
Biological sex: AllType: InterventionalSponsor: Helen Keller Eye Research FoundationUpdated: Jul 1, 2026Locations: 5
Eligibility criteria

No contraindications to laser retinopexy surgery per local site criteria. [+4]

Presence of media opacity (for example, dense cataract, corneal scar) or poor pu... [+20]