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Condition / disease
Location
Status: Not yet recruiting

The Impact of Ventilator Synchrony on Muscle Relaxant Consumption and Surgeon Satisfaction During Laparoscopic Cholecystectomy.

The goal of this clinical trial is to investigate the Impact of adding SIMV Synchronization to our standard PCV-VG mode of ventilation on muscle relaxant consumption, the frequency of relaxant top-ups and surgeon satisfaction during Laparoscopic Cholecystectomy surgeries in ASA I\&II. The main question it aims to answer is do Ventilator synchrony (PCV-VG+SIMV) reduces muscle relaxant consumption and improves surgeon satisfaction by minimizing the perception of inadequate paralysis? Primary hypothesis: Ventilator synchrony (PCV-VG+SIMV) reduces muscle relaxant consumption and improves surgeon satisfaction by minimizing the perception of inadequate paralysis. Primary outcome; 1. Compare total intraoperative rocuronium consumption (mg/kg) between PCV-VG and PCV-VG + SIMV 2. To determine the frequency of additional muscle relaxant requests

Participants needed: 60
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Hitham Mohammed Aly ElsayedUpdated: Jun 15, 2026Locations: 1
Eligibility criteria

Adults aged 18-60 years undergoing elective laparoscopic cholecystectomy. [+2]

Severe COPD or restrictive lung disease [+3]