Status: Recruiting
Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
The goal of this clinical trial is to learn if SHR-1701 combine with chemoradiotherapy works to treat severe CRC. Participants will take: Induction: SHR-1701 combined with CAPOX for one cycle. Radiotherapy: Short-course radiotherapy (SCRT) (25Gy/5F). Consolidation: SHR-1701 combined with CAPOX for five cycles, after which the subjects undergo TME surgery.
Participants needed: 48
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Hong QiuUpdated: Mar 17, 2026Locations: 1
Eligibility criteria
1: Sign the informed consent form and voluntarily participate in this study
Allergy to monoclonal antibody, SHR-1701, capecitabine, oxaliplatin and other pl... [+10]