Clinical trials

This randomized, parallel clinical trial with blinded outcome assessment will compare the clinical and aesthetic outcomes of polidocanol foam sclerotherapy alone versus polidocanol foam associated with long-pulse 1064 nm Nd:YAG transdermal laser in the treatment of lower-limb tributary varicose veins. The primary endpoint is venous occlusion rate at 30 days, assessed by Doppler ultrasound. Secondary outcomes include cutaneous hyperpigmentation, pain, patient satisfaction, and adverse events.

This cross-sectional observational study aims to test the original conceptual diagram of the Youth Physical Activity Promotion Model (YPAP) in Brazilian adolescents. The study evaluates the relationships among predisposing, enabling, and reinforcing correlates described in the YPAP framework and investigates how these correlates interact with one another according to the pathways proposed by the model. A convenience sample of adolescents aged 10 to 13 years will be recruited through broad public dissemination as part of a larger experimental intervention project. Data will be collected at a single time point. Instead of traditional linear analytical strategies, the study will adopt complex, flexible, and non-linear methods such as network analysis to examine how correlates interconnect and influence physical activity behavior. Secondary analyses will explore whether the structure and strength of associations differ across demographic subgroups such as sex and socioeconomic level.

Randomized controlled trial assessing the effects of a 12-week recreational football program on behavioral, psychosocial, environmental, and physical determinants of physical activity in male adolescents aged 10-13 years.