Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

A Study to Learn How Safe ACT-777991 is and How Well it Works in Adults With Non-segmental Vitiligo

The purpose of this clinical trial is to learn how well ACT-777991 works, how safe it is and how well it is tolerated by adults with non-segmental vitiligo. The main question this clinical trial aims to answer is: • Can ACT-777991 help return color to the skin of the face of adults with non-segmental vitiligo? Researchers will compare ACT-777991 to placebo (a look-alike inactive treatment that contains no medicine) to see if ACT-777991 works to treat non-segmental vitiligo. Trial participants will: * Take the trial intervention (either ACT-777991 or placebo) daily for 24 weeks. * Visit the clinic 7 times for check-up and tests.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Idorsia Pharmaceuticals Ltd.Updated: Jun 25, 2026
Eligibility criteria

F-VASI score ≥ 0.3 based on BICR at Screening. [+3]

Clinical diagnosis of other forms of vitiligo (e.g., segmental) or other hypo- o... [+5]

Status: Recruiting

Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®

This study will investigate pregnancy, neonatal, and infant outcomes in women exposed to QUVIVIQ during pregnancy compared to women unexposed to QUVIVIQ during pregnancy.

Participants needed: 785
Trial details
Age: 15-50Biological sex: FemaleType: ObservationalSponsor: Idorsia Pharmaceuticals Ltd.Updated: Dec 2, 2025Locations: 7Duration: 21 Months
Eligibility criteria

Diagnosis of insomnia disorder prior to pregnancy. [+4]

Exposure to any orexin receptor antagonist other than QUVIVIQ - including BELSOM... [+4]