Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Phase I/IIa Study of C5252 in Patients With Intracranial Tumor

This study includes phase I dose escalation part and phase IIa dose expansion part. The goal of this clinical trial is to learn if C5252 treatment is safe and well tolerated in patients with intracranial tumor and to learn preliminary efficacy of C5252. In this study, participants will be given single or multiple doses of C5252 according to protocol followed by toxicity observation, safety follow-up and long-term follow-up.

Participants needed: 36
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: ImmVira Pharma Co. LtdUpdated: Nov 21, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years. [+9]

Inability to undergo MRI examination for any reason. [+19]

Status: Recruiting

A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

This is a Phase 1/2a, open-label, study to evaluate the safety and preliminary efficacy of intratumoral T3011 given alone and in combination with intravenous pembrolizumab in partients with advanced or metastatic solid tumors.

Participants needed: 30
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: ImmVira Pharma Co. LtdUpdated: Oct 8, 2025Locations: 9
Eligibility criteria

Age 18 years or older. [+13]

Have only uninjectable tumors.. [+19]

Status: Recruiting

A Study of T3011 in Patients With BCG-Unresponsive NMIBC or BCG-Exposed, Chemotherapy-Unresponsive NMIBC

This is a Phase II clinical study to evaluate the efficacy and safety of intravesical T3011 injection in participants with BCG-unresponsive high-risk NMIBC or BCG-exposed, chemotherapy-unresponsive intermediate/high-risk NMIBC.

Participants needed: 160
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: ImmVira Pharma Co. LtdUpdated: Jul 23, 2025Locations: 2
Eligibility criteria

Male or female, aged ≥18 years at the time of signing the ICF. [+12]

Concurrent or prior history of muscle-invasive (muscularis propria) or metastati... [+27]