Health Trials

Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

IM-1021-101 is a Phase 1 study to determine the safety and effectiveness of IM-1021 in treating participants with advanced cancer.

Participants needed: 117
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Immunome, Inc.Updated: Jun 22, 2026Locations: 17
Eligibility criteria

Informed consent signed by the participant prior to conducting study-specific pr... [+16]

Previously treated with an ADC with a topoisomerase-1 inhibitor payload, except:... [+9]

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Status: Recruiting

A Phase 1 Study of 177Lu-IM-3050 in Participants With Advanced Cancer

IM-3050-101 is a Phase 1 study to determine the safety and effectiveness of 177Lu-IM-3050 in treating participants with advanced cancer.

Participants needed: 105
Trial details
Phase: Early Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Immunome, Inc.Updated: Jun 18, 2026Locations: 2
Eligibility criteria

≥18 years of age [+6]

Participant has received certain prior radiation therapy as detailed in the prot... [+4]

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Status: Recruiting

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

This study will test the safety and effectiveness of a drug called IM-1617 in participants with solid tumors. Participants will have solid tumor cancer that has spread through the body (metastatic) or cannot be removed with surgery (unresectable). This study will have two parts. Part A will test increasing doses of IM-1617 to find out the safe dose and schedule of IM-1617 for participants. Part B will use the dose and schedule found in Part A to further study the safety of IM-1617 and if it works to treat solid tumor cancers.

Participants needed: 175
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Immunome, Inc.Updated: Jun 15, 2026Locations: 1
Eligibility criteria

Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2 [+21]

Previously treated with an antibody-drug conjugate (ADC) with a topoisomerase-1... [+6]

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Status: Recruiting

A Relative Bioavailability and Bioequivalence Study of Varegacestat in Healthy Participants

This is an open-label, randomized, crossover study to evaluate the relative bioavailability (rBA) and bioequivalence (BE) of a test capsule formulation of varegacestat compared to reference capsules formulation under fasting conditions.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Immunome, Inc.Updated: Jun 8, 2026Locations: 1
Eligibility criteria

Healthy, adult, female of non childbearing potential or male, 18 to 55 years of... [+5]

Is mentally or legally incapacitated or has significant emotional problems at th... [+11]

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