Clinical trials

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Condition / disease
Location
Status: Recruiting

Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy

This clinical trial's goal is to evaluate if the IRL757 is safe and has a good tolerability in participants with Parkinson's disease and experiencing apathy (a lack of interest or motivation). In addition, the trial is aiming to learn if IRL757 has effects on the symptoms of Parkinson's disease. Researchers will compare the effects of IRL757 to a placebo (a look-alike substance that contains no drug). Participants who fit the study criteria will be treated with the study drug (either the active drug IRL757 or placebo) for 12 weeks and will visit the clinic at 5 defined timepoints for check-ups and tests. A follow-up call after the end of treatment will be done 4 weeks after the last study drug intake.

Participants needed: 75
Trial details
Phase: Phase 1, Phase 2Age: 50-90Biological sex: AllType: InterventionalSponsor: Integrative Research Laboratories ABUpdated: Mar 10, 2026Locations: 13
Eligibility criteria

Male and female participants between 50 and 90 years of age, inclusive, with dia... [+8]

Any active, current psychiatric comorbidity (such as major depressive disorder,... [+39]