Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

This study is designed to support evidence-based practice and optimal care by evaluating how different configurations of two types of carbon fiber custom dynamic orthoses (CDOs) influences outcomes following traumatic lower extremity injury.

Participants needed: 35
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Jason WilkenUpdated: Jan 15, 2026Locations: 5
Eligibility criteria

Between the ages of 18 and 65 [+7]

Pain greater than 8/10 at rest [+10]

Status: Recruiting

The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses

Carbon fiber custom dynamic orthoses (CDOs) improve function, reduce pain, and offload the foot and ankle. CDOs include a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that bends to store and return energy, and a semi-rigid carbon fiber footplate. The purpose of this study is to determine the effect of CDO use and CDO footplate stiffness on foot loading, limb mechanics, pain, and comfort.

Participants needed: 20
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Jason WilkenUpdated: Dec 31, 2025Locations: 1
Eligibility criteria

Between the ages of 18 and 65 [+5]

Diagnosed with a moderate or severe brain injury [+8]