Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Neoadjuvant Chemoimmunotherapy or Chemoradiotherapy in ESCC

This study was a single-arm, two-cohort, phase II trial aimed at evaluating the efficacy and safety of FAPI-PET/CT response for guiding the selection of neoadjuvant treatment modes after chemotherapy combined with immunotherapy.

Participants needed: 66
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Ji YonglingUpdated: Feb 4, 2026Locations: 1
Eligibility criteria

Be able to understand and voluntarily provide written informed consent before an... [+8]

A history of malignant tumors within the past five years prior to registration (... [+11]

Status: Recruiting

Radiation Therapy Followed by Tislelizumab and Anlotinib Aeoadjuvant/Adjuvant Therapy for Stage II-IIIA NSCLC

This study is a single-center, prospective, single-arm exploratory clinical study of hypofractionated radiotherapy followed by tislelizumab and anlotinib neoadjuvant and adjuvant therapy. It is designed for patients with stage II-IIIA non-small cell lung cancer. The efficacy and safety of hypofractionated radiotherapy sequential tislelizumab and anlotinib in the neoadjuvant and adjuvant treatment of stage II-IIIA non-small cell lung cancer are observed. Finally, it provides new evidence-based medical evidence for the perioperative treatment of non-small cell lung cancer.

Participants needed: 20
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Ji YonglingUpdated: Jul 10, 2025Locations: 1
Eligibility criteria

(1) Aged 18-75 years old; [+10]

(1) The location of the primary tumor was assessed by the radiologist and consid... [+16]

Status: Not yet recruiting

Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer

This is the first prospective clinical study to evaluate the efficacy and safety of induction chemoimmunotherapy followed by carbon ion radiotherapy and consolidation immunotherapy in patients with unresectable locally advanced non-small cell lung cancer (NSCLC). Based on this prospective study, tumor tissue, blood, urine, and stool samples from participants will be collected and analyzed to identify predictive markers of treatment response.

Participants needed: 34
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Ji YonglingUpdated: Jun 25, 2025Locations: 1
Eligibility criteria

Unresectable, locally advanced non-small cell lung cancer (according to the 8th... [+2]

Histological evidence of small cell lung cancer or other primary malignancies [+3]