Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Prospective HemorrhoIdaL EmboliSation (PILES) Registry

The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy. The main question it aims to answer are: 1\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months? Participants will: * Undergo HAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.

Participants needed: 1,200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Joint & Vascular InstituteUpdated: Jun 12, 2026Locations: 1Duration: 5 Years
Eligibility criteria

Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to...

Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

Status: Recruiting

geniculaR Artery eMBolization for Knee Osteoarthritis (RAMBO) Registry

The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of genicular artery embolization (GAE) for knee osteoarthritis in adults aged 18 years or older with symptomatic KOA that has not responded to medical therapy. The main questions it aims to answer are: 1. Does GAE lead to sustained improvement in pain (WOMAC, VAS) and quality-of-life scores over 12-36 months? 2. What patient or procedural factors are associated with better outcomes after GAE? Participants will: * Undergo GAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.

Participants needed: 1,200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Joint & Vascular InstituteUpdated: Jun 12, 2026Locations: 1Duration: 5 Years
Eligibility criteria

Adults (≥18 years) with symptomatic KOA refractory to medical therapy, referred...

Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

Status: Recruiting

Achilles Tendinopathy Embolization

The goal of this clinical trial is to learn determine the feasibility of arterial embolization using Lipiodol emulsion to safely and effectively treat chronic Achilles tendon pain due to Achilles tendinopathy in adults aged 25 to 80. The main questions it aims to answer are: 1. Does this procedure successfully reduce chronic Achilles tendon pain as measured by the Visual Analog Scale (VAS) over 12 months? 2. How safe is the procedure, specifically regarding the frequency of serious medical problems or adverse events related to the device? Participants will: * Undergo a minimally invasive procedure where a doctor uses a small tube (catheter) to inject a temporary blocking agent (LipioJoint) into specific blood vessels supplying the Achilles tendon. * Receive a phone call one day after the procedure to check for early side effects. * Participate in four follow-up visits over the course of one year (at 1, 3, 6, and 12 months). Complete pain intensity surveys (VAS) and report any changes in their use of other therapies or medications during these visits.

Participants needed: 10
Trial details
Phase: Phase 1Age: 25-80Biological sex: AllType: InterventionalSponsor: Joint & Vascular InstituteUpdated: Apr 23, 2026Locations: 1
Eligibility criteria

Age ≥ 25 years [+4]

Achilles tendon pain caused by acute fracture, recent trauma, inflammatory condi... [+7]

Status: Recruiting

Lateral Plantar Artery Embolization For Plantar Fasciitis

The goal of this clinical trial is to learn if lateral plantar artery embolization using Lipiodol can safely and effectively treat chronic heel pain due to plantar fasciitis in adults aged 25 to 80. The main questions it aims to answer are: Does this procedure successfully reduce chronic heel pain as measured by the Visual Analog Scale (VAS) over 12 months? How safe is the procedure, specifically regarding the frequency of serious medical problems or adverse events related to the device? Participants will: Undergo a minimally invasive procedure where a doctor uses a small tube (catheter) to inject a temporary blocking agent (LipioJoint) into specific blood vessels in the foot. Receive a phone call one day after the procedure to check for early side effects. Participate in four follow-up telehealth visits over the course of one year (at 1, 3, 6, and 12 months). Complete pain intensity surveys (VAS) and report any changes in their use of other therapies or medications during these visits.

Participants needed: 10
Trial details
Phase: Phase 1Age: 25-80Biological sex: AllType: InterventionalSponsor: Joint & Vascular InstituteUpdated: Feb 9, 2026Locations: 1
Eligibility criteria

Age ≥ 25 years [+4]

Heel pain caused by acute fracture, recent trauma, inflammatory conditions, musc... [+7]