Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma

The purpose of this study is to is to determine the effects (good and bad) of Zanubrutinib in Combination with Pola-R-CHP and High-dose Methotrexate in patients with Secondary Central Nervous System (CNS) Lymphoma.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Juan P. Alderuccio, MDUpdated: May 14, 2026Locations: 1
Eligibility criteria

Men and women ≥ 18 years of age on the day of signing the informed consent form... [+19]

Primary CNS lymphoma without evidence of systemic lymphoma. [+28]

Status: Recruiting

Loncastuximab Tesirine in Combination With Rituximab in Patients With Relapsed or Refractory Follicular Lymphoma

The purpose of this research is to see if Loncastuximab Tesirine in combination with Rituximab will result in higher complete response rate when given to treat follicular lymphoma.

Participants needed: 100
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Juan P. Alderuccio, MDUpdated: Mar 23, 2026Locations: 5
Eligibility criteria

Men and women ≥ 18 years of age. [+23]

FL grade 3B or transformed FL. [+10]