Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure

The EMPA-AHF trial is a multicentre, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of early initiation of once-daily oral empagliflozin 10 mg in patients hospitalized for patients with acute heart failure (AHF) who are at a high risk of adverse events.

Participants needed: 444
Trial details
Phase: Phase 3Age: 20+Biological sex: AllType: InterventionalSponsor: Juntendo UniversityUpdated: Feb 13, 2026Locations: 69
Eligibility criteria

Age of ≥20* [+1]

eGFR <20 mL/min/1.73m2 at the time of admission [+29]

Status: Recruiting

Efficacy and Safety With Early Treatment of Finerenone in Hospitalized Patients With Heart Failure

FACILITATE-HF is a multicenter, randomized, double-blind, placebo-controlled trial designed to determine whether initiation of finerenone during the early phase of hospitalization has beneficial effects in patients with AHF who have left ventricular ejection fraction 40% or more.

Participants needed: 550
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Juntendo UniversityUpdated: Feb 11, 2026Locations: 21
Eligibility criteria

Patients ≥18 years of age, male or female<br> [+11]

Estimated glomerular filtration rate (eGFR) <25 mL/min/1.73m2 by CKD-EPI Creatin... [+26]