Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease

This study is a randomized, double-blind, placebo-controlled trial specifically designed to evaluate the preliminary feasibility, initial efficacy and safety of SGLT2 inhibitors for treating NAFLD in adolescents with obesity.

Participants needed: 40
Trial details
Phase: Phase 2Age: 16-20Biological sex: AllType: InterventionalSponsor: Justin RyderUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

BMI >30 kg/m2 or >95th BMI-Percentile [+12]

ALT > 250U/L at screening [+33]

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Status: Not yet recruiting

SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver Disease

This study is a randomized, double-blind, placebo-controlled trial specifically designed to evaluate the preliminary feasibility, initial efficacy and safety of SGLT2 inhibitors for treating NAFLD in adolescents with obesity.

Participants needed: 40
Trial details
Phase: Phase 2Age: 12-20Biological sex: AllType: InterventionalSponsor: Justin RyderUpdated: Jan 20, 2026Locations: 1
Eligibility criteria

Age: 12 to <20 years old [+9]

ALT > 250U/L at screening [+34]

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