Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Can Betamethasone Given After Birth Help Extremely Premature Babies Come Off Breathing Support Safely and Effectively?

The goal of this study is to determine if giving a steroid medication (specifically, betamethasone) after birth can help extremely premature babies (born before 28 weeks) come off breathing machines safely and reduce their risk of chronic lung disease associated with prematurity. Only babies who meet treatment criteria will receive this medication. Babies who do not meet treatment criteria will not receive medication. The main questions it aims to answer are: * Does betamethasone make it easier for babies to come off a breathing machine? * Does betamethasone cause any harmful side effects on growth or development? All babies in this study will: * Receive standard NICU care, with or without betamethasone * Have their progress, growth, and development followed over time

Participants needed: 100
Trial details
Phase: Phase 2Age: Up to 28Biological sex: AllType: InterventionalSponsor: Khang NguyenUpdated: Mar 3, 2026Locations: 1
Eligibility criteria

Infants born at less than 28 weeks gestation age [+1]

Infants with major congenital or chromosomal abnormalities. [+2]