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Condition / disease
Location
Status: Recruiting

Vericiguat in Decompensated Cardiac Failure: Clinical Insights on Addition to Guidelines Derived Medical Therapy-VERCIG Trial

This study will compare the outcomes of Vericuguat and placebo in patient with decompensated heart failure . This study will carry out after approval from IERB. Seventy patients fulfilling the inclusion criteria will be enrolled from emergency department. Informed consent will be taken from attendants. A detailed history including name, age, gender, duration of heart failure, history of alcoholism, smoking, diabetes, hypertension, EF at baseline and NYHA class will be noted. Patients will be randomly divided in two groups by using lottery method. Outcomes will be assessed at in terms of hospitalization for heart failure, death from cardiovascular event and side effects.

Participants needed: 130
Trial details
Phase: Phase 1Age: 25-65Biological sex: AllType: InterventionalSponsor: Khawaja Danish AliUpdated: Mar 2, 2026Locations: 1
Eligibility criteria

Patients diagnosed with decompensated heart failure (patients with left ventricu...

Patients with blood pressure <100 mmHg; [+2]