Clinical trials

6

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

This study will have two Phases: Phase 1a and Phase 1b. The goals of this clinical study are to learn more about the study drug KITE-363, by evaluating its safety, tolerability and efficacy in participants with relapsed/refractory autoimmune neurologic diseases. The primary objectives of this study are: * To evaluate the safety and tolerability of KITE-363 in participants with autoimmune neurologic diseases * To determine the recommended dose for Phase 1b. * To evaluate the preliminary efficacy of KITE-363 in participants with autoimmune neurologic diseases.

Participants needed: 52
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Kite, A Gilead CompanyUpdated: Jul 1, 2026Locations: 6
Eligibility criteria

Participants must agree to use protocol-specified method(s) of contraception whe... [+18]

History or presence of central nervous system (CNS) or peripheral nervous system... [+9]

Status: Recruiting

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

The goal of this clinical study is to learn more about the safety and effectiveness of the study drugs, KITE-363 and KITE-753, in participants with relapsed and/or refractory B-cell lymphoma.

Participants needed: 247
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Kite, A Gilead CompanyUpdated: Jun 29, 2026Locations: 26
Eligibility criteria

Relapsed and/or refractory B-cell lymphoma (R/R BCL). [+2]

History of malignancy other than nonmelanoma skin cancer or carcinoma in situ (e... [+11]

Status: Recruiting

Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy

The goal of this clinical study is to compare the study drug KITE-753 versus axicabtagene ciloleucel (axi-cel) in adult participants with relapsed or refractory (r/r) large B-cell lymphoma (LBCL) after one prior line of therapy. The primary objective of this study is to evaluate the efficacy of KITE-753 versus axicabtagene ciloleucel.

Participants needed: 550
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Kite, A Gilead CompanyUpdated: Jun 16, 2026Locations: 2
Eligibility criteria

Progressive disease (PD) and/or Deauville score of 5 (irrespective of the respon... [+21]

Prior CAR T-cell therapy or other cell-based therapy. [+22]

Status: Available

Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Axicabtagene Ciloleucel

The goal of this study is to provide access to axicabtagene ciloleucel for patients diagnosed with a disease approved for treatment with axicabtagene ciloleucel, that is otherwise out of specification for commercial release.

Trial details
Age: 18+Biological sex: AllType: Expanded AccessSponsor: Kite, A Gilead CompanyUpdated: Jun 12, 2026Locations: 128
Eligibility criteria

Have commercially manufactured axicabtagene ciloleucel that does not meet commer... [+5]

History of severe immediate hypersensitivity to any drugs or metabolites of simi... [+2]

Status: Recruiting

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, including an anti-CD38 monoclonal antibody and an immunomodulatory drug. The primary objective of this study is to compare the efficacy of anitocabtagene autoleucel versus SOCT in participants with RRMM.

Participants needed: 450
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Kite, A Gilead CompanyUpdated: May 7, 2026Locations: 124
Eligibility criteria

Documented historical diagnosis of multiple myeloma (MM) [+7]

Prior B-cell maturation antigen (BCMA)-targeted therapy [+13]

Status: Available

Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Brexucabtagene Autoleucel

The goal of this study is to provide access to brexucabtagene autoleucel for patients diagnosed with a disease approved for treatment with brexucabtagene autoleucel, that is otherwise out of specification for commercial release.

Trial details
Age: 18+Biological sex: AllType: Expanded AccessSponsor: Kite, A Gilead CompanyUpdated: Apr 8, 2026Locations: 44
Eligibility criteria

Have commercially manufactured brexucabtagene autoleucel that does not meet comm... [+5]

History of severe immediate hypersensitivity to any drugs or metabolites of simi... [+2]