Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)

This is a multi-center, non-randomized, open-label, dosimetry and dose-escalation, cohort-expansion study of LNTH-2403 administered to subjects with relapsed / refractory (R/R) osteosarcoma. This study consists of 2 phases: (1) a dosimetry and dose escalation phase; and (2) a cohort expansion phase.

Participants needed: 55
Trial details
Phase: Phase 1, Phase 2Age: 12+Biological sex: AllType: InterventionalSponsor: Lantheus Medical ImagingUpdated: May 1, 2026Locations: 2
Eligibility criteria

Histopathologic documented diagnosis of R/R osteosarcoma [+15]

Known allergies, hypersensitivity, or intolerance to LNTH-2403 and/or its excipi... [+13]

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Status: Recruiting

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

This is a multicenter, open-label, prospective Phase 1/2a study to assess safety and tolerability, establish dosimetry and to identify an optimal imaging dose (radioactivity) and imaging time window of 64Cu-LNTH-1363S, and to compare its imaging biodistribution with FAP expression by IHC in patients with sarcomas or GIT cancers. The study will be conducted in 2 parts (Part 1 and Part 2).

Participants needed: 26
Trial details
Phase: Phase 1, Phase 2Age: 15+Biological sex: AllType: InterventionalSponsor: Lantheus Medical ImagingUpdated: Aug 12, 2025Locations: 5
Eligibility criteria

Patient must be ≥ 15 years of age and must have provided written informed consen... [+13]

Unlikely to comply with protocol procedures, restrictions and requirements as ju... [+16]

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