Status: Recruiting
Melatonin Versus Placebo for Bipolar Disorder
The objective with this study is to conduct a 6-month RCT comparing effects of add-on melatonin versus add-on placebo on mood stabilisation and other critical patient outcomes in patients with BD and to test whether principal effects are antimanic, antidepressant and/or prophylactic against relapse
Participants needed: 200
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Lars Vedel KessingUpdated: May 12, 2026Locations: 1
Eligibility criteria
Bipolar disorder with diagnosis confirmed by SCAN interview [+3]
Past intolerance to melatonin (allergic reactions) [+2]