Status: Not yet recruiting
A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor
This was a multicenter, open PHASE I study of LTC004 in Combination With Cyclophosphamide and Fludarabine in Patients With Advanced/Metastatic Malignancies Tumor, the study design consisting of 2 phases: Phase Ia (Phase Ia dose escalation) and Phase Ib (Phase Ib expansion). The objective of this study was to evaluate combination safety, tolerability, pharmacokinetic,pharmacodynamics characteristics, and initial efficacy in advanced malignant tumors.
Participants needed: 48
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: LetolabUpdated: Feb 26, 2024
Eligibility criteria
Aged 18 to 75 years； [+8]
History of severe hypersensitivity reactions to other mAbs. [+25]