Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers

This study will evaluate Matrion™ (LifeNet Health, Inc., Virginia Beach, VA), a placental membrane product, as a treatment for diabetic foot ulcers compared to conventional wound care. Matrion is derived from donated human birth tissue and includes both the amniotic and chorionic layers, along with the trophoblast layer. It is minimally processed using a proprietary decellularization method and terminally sterilized to ensure the membrane is acellular and sterile, making it suitable for surgical applications.

Participants needed: 120
Trial details
Age: 21-80Biological sex: AllType: InterventionalSponsor: LifeNet HealthUpdated: Dec 10, 2025Locations: 18
Eligibility criteria

Be male or female and aged between 21 and 80 years at the time of informed conse... [+14]

Be pregnant or lactating [+19]

Status: Recruiting

Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry

Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: LifeNet HealthUpdated: Apr 2, 2025Locations: 4Duration: 24 Months
Eligibility criteria

Be male or female, ≥18 years of age at the time of graft placement [+4]

Be participating in a study of another investigational drug or device [+5]

Status: Recruiting

Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care

Prospective registry and retrospective data collection study to assess the efficacy and safety of Vivigen Cellular Bone Matrix (Vivigen) in orthopaedic trauma patients who require bone grafting in the acute, delayed, non-union fracture as well as use in fusion procedure settings.

Participants needed: 250
Trial details
Biological sex: AllType: ObservationalSponsor: LifeNet HealthUpdated: Apr 2, 2025Locations: 4Duration: 24 Months
Eligibility criteria

Any skeletally mature patient treated with Vivigen bone graft in the setting of...

Patients unable to understand either an English or Spanish consent will be exclu... [+1]