Clinical trials

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Condition / disease
Location
Status: Recruiting

Effect of Intensive Lipid-Lowering Therapy on Coronary Atherosclerotic Plaque Progression in Young and Middle-Aged Patients With Chronic Coronary Syndrome

This is a multicenter, open-label, parallel-group, randomized trial to determine if intensive lipid-lowering therapy (goal for LDL-C \<1.0 mmol/L and ≥50% reduction frome baseline) could delay progression of coronary atherosclerotic obstructive leisions compared with guideline recommended lipid-lowering therapy (goal for LDL-C \<1.8 mmol/L and ≥50% reduction frome baseline) among participants between 18-60 years old with non-invasively managed chronic coronary syndrome (at least one lesion with a 50%-70% stenosis).

Participants needed: 766
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Liu yongUpdated: Dec 17, 2025Locations: 7
Eligibility criteria

Left main coronary artery disease or severe three-vessel disease; [+7]