Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Evaluate the Efficacy and Safety of LP-003 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group Phase II clinical trial. Its primary objective is to explore and preliminarily evaluate the efficacy and safety of LP-003 Injection in the treatment of participants with chronic rhinosinusitis with nasal polyps (CRSwNP), as well as to investigate its pharmacokinetic (PK), pharmacodynamic (PD) profiles, and immunogenicity.

Participants needed: 150
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Longbio PharmaUpdated: Feb 6, 2026Locations: 1
Eligibility criteria

Capable of understanding the study and voluntarily signing the Informed Consent... [+10]

Concurrent other nasal diseases or nasal symptoms; [+15]

Status: Not yet recruiting

Efficacy and Safety of LP-005 Injection in Patients With Complement-Mediated Kidney Disease

This is a multicenter, open-label, proof-of-concept, phase Ⅱ adaptive basket clinical trial designed to evaluate the efficacy, safety, and pharmacokinetic profile of LP-005 Injection as add-on therapy to standard treatment in patients with complement-mediated renal diseases.

Participants needed: 46
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Longbio PharmaUpdated: Jan 23, 2026Locations: 1
Eligibility criteria

Males or females aged 18 to 65 years at screening. [+4]

Pregnant or lactating female. [+8]

Status: Recruiting

Efficacy, Safety, and Pharmacokinetics of LP-003 Injection in Allergic Asthma Patients

This is a multicenter, randomized, masked, active and placebo controlled, Phase II clinical study to evaluate the efficacy, safety, and pharmacokinetics of LP-003 injection in adult patients with moderate to severe persistent allergic asthma.

Participants needed: 200
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Longbio PharmaUpdated: Jan 15, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years and ≤ 75 years, no gender restriction; [+9]

Allergic to the investigational product and its excipients or Xolair® ; [+17]

Status: Not yet recruiting

Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

This is an extension study for patients who have completed a prior P10-LP005-02 clinical study. The aim of this study is to evaluate the long-term safety, efficacy, and pharmacokinetics of LP-005 injection in adult patients with paroxysmal nocturnal hemoglobinuria (PNH).

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Longbio PharmaUpdated: Dec 5, 2025Locations: 1
Eligibility criteria

Patients have fully understood the trial, have voluntarily agreed to participate... [+3]

Patients who have not completed the treatment of the Phase II clinical trial (P1... [+3]