Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism

The purpose of this study is to investigate the efficacy and safety of canvuparatide administered as a once-weekly (QW) treatment to adult study participants with hypoparathyroidism (HypoPT).

Participants needed: 160
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: MBX BiosciencesUpdated: Jul 13, 2026Locations: 2
Eligibility criteria

Is an adult ≥18 years of age. [+4]

Has a known history of pseudohypoparathyroidism [+4]

Status: Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

The purpose of this study is to evaluate the safety and tolerability of single and multiple subcutaneous (SC) doses of MBX 4291 in adults with obesity.

Participants needed: 124
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: MBX BiosciencesUpdated: Jun 9, 2026Locations: 4
Eligibility criteria

Age of >18 to ≤65 years at the time of signing the informed consent. [+2]

History of, or currently active, significant illness or medical disorders that i... [+3]