Clinical trials

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Condition / disease
Location
Status: Recruiting

A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections

The goal of this Phase 1 clinical trial is to learn about the safety profile of Amicidin-β topical solution applied directly into infected surgical or traumatic wounds during a surgical procedure. The main questions it aims to answer are: 1. Is Amicidin-β topical solution safe to test in larger clinical trials? 2. Is Amicidin-β topical solution absorbed into the bloodstream from local wound application? 3. Is Amicidin-β topical solution easy for the surgeon to use? Participants will receive either standard of care alone, or standard of care with intrawound Amicidin-β topical solution for the management of their wound infection. Researchers will compare these two groups (standard of care alone to standard of care with Amicidin-β topical solution) to see if there are any study drug-related adverse effects.

Participants needed: 44
Trial details
Phase: Phase 1Age: 18-79Biological sex: AllType: InterventionalSponsor: Macro Biologics, Inc.Updated: May 6, 2026Locations: 4
Eligibility criteria

Body Mass Index between 18.5 kg/square meter and 39.9kg/square meter [+8]

Surgical or traumatic wound associated with surrounding cellulitis extending ≥10... [+15]