Status: Recruiting
Fecal Microbiota Transplantation for IBS
The purpose of this study is to learn the efficacy and safety of fecal microbiota transplantation (FMT) using stool from a donor with low proteolytic activity and containing the bacteria Alistipes putredinis in patients with irritable bowel syndrome (IBS) and high proteolytic activity. Proteolytic activity is the breakdown of proteins into smaller polypeptides or amino acids.
Participants needed: 43
Trial details
Phase: Phase 2Age: 18-70Biological sex: FemaleType: InterventionalSponsor: Madhusudan (Madhu) Grover, MBBSUpdated: May 8, 2026Locations: 1
Eligibility criteria
IBS defined by Rome IV criteria [+3]
Immune deficiency or treatment with immunosuppressive medications [+12]